Oh definitely. There are MULTIPLE facets of Plague they could go with if they regret the rot/decay/gross shit. They could go with the barren wastelands of red clay and the green sky with stunted, warped plants; endless bone yards and gorges filled with simple green sludge (radioactive green to imply virulence), and exactly- use Mad Max survivalist shit to amp up that Survival At All Costs theme.
Re: Mire revamp ahoy!